岗位要求:
1.生物学/医学相关专业硕士以上学历,具有基本的细胞实验、小鼠实验、动物繁育及组织切片等相关工作经验者优先;
2.负责实验室日常运作、试剂耗材采购、试剂配制、财务报销等工作。
岗位待遇:
1.薪资待遇:按照上海交通大学附属第一人民医院常规招聘,享受五险一金等相关福利及有竞争力的薪酬待遇;
2.表现优秀且有意向者可优先推荐免试读研读博;
3.提供优质医疗资源和执业健康管理。
导师介绍
1.简介:
孔贵萍 PhD
上海交通大学医学院附属第一人民医院,临床研究院,课题组组长
国家海外优秀青年科学基金获得者(2025)
上海市领军人才项目(海外)获得者
英国伦敦帝国理工学院,助理研究员
德国图宾根大学Hertie研究所,博士
2.研究方向:
神经损伤与修复
3.原创性科研成果:
(1)发现CD8+ T细胞介导的衰老抑制脊髓损伤修复的新机制(Neuron, 2025);
(2)揭示了周围神经损伤下衰老抑制神经损伤后修复的细胞交互机制(Science, 2022);
(3)发现了抑制感觉神经元轴突再生的重要代谢调控分子(Nature Metabolism, 2020)。
4.近五年代表性文章
1) Kong G, Song Y, Yan Y, Calderazzo SM, Saddala MS, De Labastida Rivera F, Cherry JD, Eckman N, Appel EA, Velenosi A, Swarup V, Kawaguchi R, Ng SS, Kwon BK, Gate D, Engwerda CR, Zhou L, Di Giovanni S. Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing. Neuron 113?684-700 (2025).
2) Yan Y, Antolin N, Zhou L, Xu L, Vargas IL, Gomez CD, Kong G, Palmisano I, Yang Y, Chadwick J, Muller F, Bull AMJ, Lo Celso C, Primiano G, Servidei S, Perrier JF, Bellardita C, Di Giovanni S. Macrophages excite muscle spindles with glutamate to bolster locomotion. Nature 637, 698-707 (2025).
3) Palmisano I, Liu T, Gao W, Zhou L, Merkenschlager M, Mueller F, Chadwick J, Rivalta RT, Kong G, King JWD, Jibury EA, Yan YY, Carlino A, Collison B, De Vitis E, Gongala S, De Virgiliis F, Wang Z, Di Giovanni S. Three-dimensional chromatin mapping of sensory neurons reveals that promoter?enhancer looping is required for axonal regeneration. P Natl Acad Sci USA 121 (2024).
4) De Virgiliis F, Mueller F, Palmisano I, Chadwick JS, Luengo-Gutierrez L, Giarrizzo A, Yan Y, Danzi MC, Picon-Munoz C, Zhou L, Kong G, Serger E, Hutson TH, Maldonado-Lasuncion I, Song Y, Scheiermann C, Brancaccio M, Di Giovanni S. The circadian clock time tunes axonal regeneration. Cell Metabolism 35, 2153-2164 e2154 (2023).
5) Muller F*, De Virgiliis F*, Kong G*, Zhou L*, Serger E, Chadwick J, Sanchez-Vassopoulos A, Singh AK, Eswaramoorthy M, Kundu TK, Di Giovanni S. CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability. PLOS Biology 20, e3001310 (2022). (Co-first author)
6) Serger E, Luengo-Gutierrez L, Chadwick JS, Kong G, Zhou L, Crawford G, Danzi MC, Myridakis A, Brandis A, Bello AT, Muller F, Sanchez-Vassopoulos A, De Virgiliis F, Liddell P, Dumas ME, Strid J, Mani S, Dodd D, Di Giovanni S. The gut metabolite indole-3 propionate promotes nerve regeneration and repair. Nature 607, 585-592 (2022).
7) Zhou L*, Kong G*, Palmisano I, Cencioni MT, Danzi M, De Virgiliis F, Chadwick JS, Crawford G, Yu Z, De Winter F, Lemmon V, Bixby J, Puttagunta R, Verhaagen J, Pospori C, Lo Celso C, Strid J, Botto M, Di Giovanni S. Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline. Science 376, eabd5926 (2022). (Co-first author)
8) Kong G, Zhou L, Freiwald A, Shkura K, Di Giovanni S. Purification of mouse axoplasmic proteins from dorsal root ganglia nerves for proteomics analysis. STAR Protocols 3, 101166 (2022). (Co-corresponding author)
9) Kong G, Zhou L, Serger E, Palmisano I, De Virgiliis F, Hutson TH, McLachlan E, Freiwald A, La Montanara P, Shkura K, Puttagunta R, Di Giovanni S. AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury. Nature Metabolism 2, 918-933 (2020).
10) La Montanara P, Hervera A, Baltussen LL, Hutson TH, Palmisano I, De Virgiliis F, Kong G, Chadwick J, Gao Y, Bartus K, Majid QA, Gorgoraptis N, Wong K, Downs J, Pizzorusso T, Ultanir SK, Leonard H, Yu H, Millar DS, Istvan N, Mazarakis ND, Di Giovanni S. Cyclin-dependent?like kinase 5 is required for pain signaling in human sensory neurons and mouse models. Science Translation Medicine 12(2020).